Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702215 | 1.00 | L3MBTL1 (0.40) | L3MBTL1SIGMAR1CYP2C19KMT2ATSHR | |
| SCHEMBL6541752 | 0.88 | L3MBTL1 (0.45) | L3MBTL1SIGMAR1CYP2C19KMT2ATSHR | |
| SCHEMBL9016970 | 0.83 | SMPD2 (0.37) | L3MBTL1SIGMAR1CYP2C19KMT2ATSHR | |
| SCHEMBL9016973 | 0.83 | SMPD2 (0.37) | L3MBTL1SIGMAR1CYP2C19KMT2ATSHR | |
| SCHEMBL2343211 | 0.81 | TSHR (0.59) | L3MBTL1SIGMAR1CYP2C19KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL3792219 | 0.80 | TSHR (0.58) | L3MBTL1SIGMAR1CYP2C19KMT2ATSHR | |
| SCHEMBL12765200 | 0.74 | ALDH1A1 (0.37) | L3MBTL1SIGMAR1CYP2C19KMT2ATSHR | |
| SCHEMBL9463178 | 0.74 | AOC3 (0.44) | L3MBTL1SIGMAR1CYP2C19KMT2ACYP1A2 | |
| SCHEMBL2865598 | 0.74 | SIGMAR1 (0.50) | L3MBTL1SIGMAR1CYP2C19KMT2ATSHR | |
| SCHEMBL30966945 | 0.74 | SIGMAR1 (0.50) | L3MBTL1SIGMAR1CYP2C19KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514333-A2 | Substituted 1,4-diamino-2-butene stabilizers and stabilized compositions | CIBA-GEIGY AG (CH) | 1992-11-19 | — | — | EP | claimed |