Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39114 | 1.00 | KCNH2 (0.38) | KCNH2MAOBKDM4EMTNR1AMTNR1B | |
| SCHEMBL9429468 | 0.84 | MEN1 (0.49) | KCNH2MAOBKDM4EL3MBTL1CYP1A2 | |
| SCHEMBL9016966 | 0.83 | TK1 (0.43) | KCNH2MAOBALDH1A1CYP2C19TSHR | |
| SCHEMBL9016968 | 0.83 | TK1 (0.43) | KCNH2MAOBALDH1A1CYP2C19TSHR | |
| SCHEMBL39946 | 0.81 | ESR1 (0.44) | KCNH2KDM4EALDH1A1ESR1CYP1A2 | |
| SCHEMBL9818045 | 0.81 | ESR1 (0.44) | KCNH2KDM4EALDH1A1ESR1CYP1A2 | |
| SCHEMBL5077351 | 0.80 | KDM4E (0.37) | KCNH2KDM4EMTNR1AMTNR1BNPSR1 | |
| SCHEMBL2227806 | 0.80 | MAPT (0.38) | KCNH2KDM4EMTNR1AMTNR1BTAAR1 | |
| SCHEMBL5077354 | 0.80 | KDM4E (0.37) | KCNH2KDM4EMTNR1AMTNR1BNPSR1 | |
| SCHEMBL3293008 | 0.79 | KCNH2 (0.35) | KCNH2KDM4EMTNR1AMTNR1BTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514333-A2 | Substituted 1,4-diamino-2-butene stabilizers and stabilized compositions | CIBA-GEIGY AG (CH) | 1992-11-19 | — | — | EP | claimed |
| JP-3093751-A | — | — | None | — | — | JP | disclosed |
| US-5492954-A | STABILIZE LUBRICANTS AND SYNTHETIC POLYMERS AGAINST THE DELETERIOUS EFFECTS OF OXYGEN AND HEAT | CIBA-GEIGY CORPORATION (US) | 1996-02-20 | — | — | US | disclosed |
| US-5391808-A | Lubricant and synthetic polymer additives for heat and oxidation resistance | CIBA-GEIGY CORPORATION (US) | 1995-02-21 | — | — | US | disclosed |
| EP-0417036-B1 | Butenyl aromatic amine stabilizers | CIBA GEIGY AG (CH) | 1994-03-09 | — | — | EP | disclosed |
| EP-0585202-A1 | N,N'-alkenylene amine/mercaptotolyl-imidazole blends as high temperature antioxidants for elastomers | CIBA-GEIGY AG (CH) | 1994-03-02 | — | — | EP | disclosed |
| US-5283367-A | Antioxidants for lubricants and polymers | CIBA-GEIGY CORPORATION (US) | 1994-02-01 | — | — | US | disclosed |
| EP-0514333-A2 | Substituted 1,4-diamino-2-butene stabilizers and stabilized compositions | CIBA-GEIGY AG (CH) | 1992-11-19 | — | — | EP | disclosed |
| JP-H0393751-A | STABILISER FOR BUTENYL AROMATIC AMINE | CIBA GEIGY AG | 1991-04-18 | — | — | JP | disclosed |
| EP-0417036-A2 | Butenyl aromatic amine stabilizers | CIBA-GEIGY AG (CH) | 1991-03-13 | — | — | EP | disclosed |