Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.35 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016983 | 1.00 | ALOX5 (0.39) | ALOX5OPRM1OPRD1OPRK1ADH1B | |
| SCHEMBL5512680 | 0.81 | ALOX5 (0.46) | ALOX5OPRM1OPRD1OPRK1ADRA1B | |
| SCHEMBL9016988 | 0.79 | OPRM1 (0.51) | OPRM1OPRD1OPRK1 | |
| SCHEMBL9016990 | 0.79 | OPRM1 (0.51) | OPRM1OPRD1OPRK1 | |
| SCHEMBL9016964 | 0.76 | OPRM1 (0.53) | OPRM1OPRD1OPRK1 | |
| SCHEMBL9016960 | 0.76 | OPRM1 (0.53) | OPRM1OPRD1OPRK1 | |
| SCHEMBL12018411 | 0.72 | CYP1A2 (0.42) | ALOX5OPRM1OPRD1OPRK1ADH1C | |
| SCHEMBL20900599 | 0.72 | CYP1A2 (0.42) | ALOX5OPRM1OPRD1OPRK1ADH1C | |
| SCHEMBL16559079 | 0.72 | CYP1A2 (0.42) | ALOX5OPRM1OPRD1OPRK1ADH1C | |
| SCHEMBL4675824 | 0.72 | ALOX5 (0.40) | ALOX5OPRM1OPRD1OPRK1ADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283367-A | Antioxidants for lubricants and polymers | CIBA-GEIGY CORPORATION (US) | 1994-02-01 | — | — | US | claimed |
| EP-0514333-A2 | Substituted 1,4-diamino-2-butene stabilizers and stabilized compositions | CIBA-GEIGY AG (CH) | 1992-11-19 | — | — | EP | claimed |
| US-5492954-A | STABILIZE LUBRICANTS AND SYNTHETIC POLYMERS AGAINST THE DELETERIOUS EFFECTS OF OXYGEN AND HEAT | CIBA-GEIGY CORPORATION (US) | 1996-02-20 | — | — | US | disclosed |
| US-5391808-A | Lubricant and synthetic polymer additives for heat and oxidation resistance | CIBA-GEIGY CORPORATION (US) | 1995-02-21 | — | — | US | disclosed |
| EP-0585202-A1 | N,N'-alkenylene amine/mercaptotolyl-imidazole blends as high temperature antioxidants for elastomers | CIBA-GEIGY AG (CH) | 1994-03-02 | — | — | EP | disclosed |
| US-5283367-A | Antioxidants for lubricants and polymers | CIBA-GEIGY CORPORATION (US) | 1994-02-01 | — | — | US | disclosed |
| US-5240976-A | For automobile, wire and cable uses | CIBA-GEIGY CORPORATION (US) | 1993-08-31 | — | — | US | disclosed |
| EP-0514333-A2 | Substituted 1,4-diamino-2-butene stabilizers and stabilized compositions | CIBA-GEIGY AG (CH) | 1992-11-19 | — | — | EP | disclosed |