Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421536 | 1.00 | TK1 (0.49) | TK1TSHRALDH1A1MAOBCNR2 | |
| SCHEMBL9016968 | 0.88 | TK1 (0.43) | TK1TSHRALDH1A1MAOBCNR2 | |
| SCHEMBL9016966 | 0.88 | TK1 (0.43) | TK1TSHRALDH1A1MAOBCNR2 | |
| SCHEMBL5073288 | 0.87 | TSHR (0.46) | TK1TSHRALDH1A1MAOBCNR2 | |
| SCHEMBL5073289 | 0.87 | TSHR (0.46) | TK1TSHRALDH1A1MAOBCNR2 | |
| SCHEMBL1931710 | 0.85 | MEN1 (0.54) | TSHRKCNH2G6PC1KDM4EOPRK1 | |
| SCHEMBL1931712 | 0.85 | MEN1 (0.54) | TSHRKCNH2G6PC1KDM4EOPRK1 | |
| SCHEMBL2565691 | 0.82 | ALDH1A1 (0.47) | TK1TSHRALDH1A1MAOBCNR2 | |
| SCHEMBL9016969 | 0.82 | CYP2D6 (0.52) | TK1TSHRALDH1A1KCNH2OPRK1 | |
| SCHEMBL516674 | 0.81 | BCHE (0.49) | TSHRALDH1A1CNR2AOC3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514333-A2 | Substituted 1,4-diamino-2-butene stabilizers and stabilized compositions | CIBA-GEIGY AG (CH) | 1992-11-19 | — | — | EP | claimed |
| US-5492954-A | STABILIZE LUBRICANTS AND SYNTHETIC POLYMERS AGAINST THE DELETERIOUS EFFECTS OF OXYGEN AND HEAT | CIBA-GEIGY CORPORATION (US) | 1996-02-20 | — | — | US | disclosed |
| US-5391808-A | Lubricant and synthetic polymer additives for heat and oxidation resistance | CIBA-GEIGY CORPORATION (US) | 1995-02-21 | — | — | US | disclosed |
| EP-0585202-A1 | N,N'-alkenylene amine/mercaptotolyl-imidazole blends as high temperature antioxidants for elastomers | CIBA-GEIGY AG (CH) | 1994-03-02 | — | — | EP | disclosed |
| US-5283367-A | Antioxidants for lubricants and polymers | CIBA-GEIGY CORPORATION (US) | 1994-02-01 | — | — | US | disclosed |
| US-5240976-A | For automobile, wire and cable uses | CIBA-GEIGY CORPORATION (US) | 1993-08-31 | — | — | US | disclosed |
| EP-0514333-A2 | Substituted 1,4-diamino-2-butene stabilizers and stabilized compositions | CIBA-GEIGY AG (CH) | 1992-11-19 | — | — | EP | disclosed |