Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | EBP | Q15125 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678223 | 0.90 | CYP2D6 (0.58) | CYP2D6LMNACYP1A2CYP2C19SLC6A2 | |
| SCHEMBL9016986 | 0.82 | TK1 (0.49) | KCNH2OPRK1TSHRALDH1A1TK1 | |
| SCHEMBL8421536 | 0.82 | TK1 (0.49) | KCNH2OPRK1TSHRALDH1A1TK1 | |
| SCHEMBL7915221 | 0.80 | CYP2D6 (0.69) | CYP2D6LMNACYP1A2CYP2C19SLC6A2 | |
| SCHEMBL4816296 | 0.80 | CYP2D6 (0.56) | CYP2D6LMNACYP1A2CYP2C19SLC6A2 | |
| SCHEMBL18589310 | 0.77 | CYP2D6 (0.56) | CYP2D6LMNACYP1A2CYP2C19SLC6A2 | |
| SCHEMBL18942412 | 0.76 | TDP1 (0.62) | CYP2D6LMNACYP1A2CYP2C19SLC6A2 | |
| SCHEMBL14855453 | 0.75 | CYP1A2 (0.50) | CYP2D6LMNACYP1A2CYP2C19SLC6A2 | |
| SCHEMBL6678833 | 0.75 | CYP2D6 (0.53) | CYP2D6LMNACYP1A2CYP2C19SLC6A2 | |
| SCHEMBL9702212 | 0.73 | L3MBTL1 (0.40) | CYP2D6LMNACYP1A2CYP2C19SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5492954-A | STABILIZE LUBRICANTS AND SYNTHETIC POLYMERS AGAINST THE DELETERIOUS EFFECTS OF OXYGEN AND HEAT | CIBA-GEIGY CORPORATION (US) | 1996-02-20 | — | — | US | disclosed |
| US-5391808-A | Lubricant and synthetic polymer additives for heat and oxidation resistance | CIBA-GEIGY CORPORATION (US) | 1995-02-21 | — | — | US | disclosed |
| EP-0585202-A1 | N,N'-alkenylene amine/mercaptotolyl-imidazole blends as high temperature antioxidants for elastomers | CIBA-GEIGY AG (CH) | 1994-03-02 | — | — | EP | disclosed |
| US-5283367-A | Antioxidants for lubricants and polymers | CIBA-GEIGY CORPORATION (US) | 1994-02-01 | — | — | US | disclosed |
| US-5240976-A | For automobile, wire and cable uses | CIBA-GEIGY CORPORATION (US) | 1993-08-31 | — | — | US | disclosed |
| EP-0514333-A2 | Substituted 1,4-diamino-2-butene stabilizers and stabilized compositions | CIBA-GEIGY AG (CH) | 1992-11-19 | — | — | EP | disclosed |