Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 3/20 | 0.31 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
| ▸ | PLAT | P00750 | 2/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | PYGL | P06737 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8742141 | 0.98 | F2 (0.31) | PLAUF2F10PLATPLG | |
| SCHEMBL31716233 | 0.74 | IKBKB (0.42) | PLAUKDM4EGLA | |
| Hydrochloric Acid SCHEMBL8742164 | 0.73 | KDM4E (0.58) | KDM4EGLA | |
| SCHEMBL8742203 | 0.73 | GSK3B (0.47) | PLAUF2F10PLATPLG | |
| Hydrochloric Acid SCHEMBL9016995 | 0.72 | CA1 (0.51) | — | |
| Hydrochloric Acid SCHEMBL9568563 | 0.72 | CA1 (0.51) | — | |
| Hydrochloric Acid SCHEMBL9017005 | 0.72 | PLAU (0.44) | PLAUF2F10PLATPLG | |
| Hydrochloric Acid SCHEMBL8742115 | 0.71 | GSK3B (0.46) | PLAUF2F10PLATPLG | |
| Hydrochloric Acid SCHEMBL9016999 | 0.71 | FADS1 (0.54) | PLAUF2F10PLATPLG | |
| SCHEMBL8634908 | 0.70 | RAB9A (0.50) | KDM4EPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690048-A1 | Ortho-amino substituted benzoylguanidines, process for their preparation, their use as medicine or diagnostic and medicines containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-03 | — | — | EP | disclosed |