Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 1/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 3/20 | 0.40 |
| ▸ | DHFR | P00374 | 2/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL901670 | 0.80 | ALDH1A1 (0.47) | ENPP3ENPP1MEN1KMT2AKDM4E | |
| SCHEMBL902558 | 0.78 | ALDH1A1 (0.45) | ENPP3ENPP1MEN1KMT2AKDM4E | |
| SCHEMBL902724 | 0.77 | SMN1; SMN2 (0.45) | MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL902184 | 0.77 | KDM4E (0.46) | MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL9594949 | 0.77 | KDM4E (0.49) | MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL9594726 | 0.76 | KDM4E (0.57) | MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL14126140 | 0.74 | KDM4E (0.62) | MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL9594668 | 0.73 | ALDH1A1 (0.46) | MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL9594126 | 0.73 | ALDH1A1 (0.46) | MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL11194565 | 0.73 | KDM4E (0.61) | MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130310411-A1 | NOVEL ACRIDINE DERIVATIVES | PHARMINOX LIMITED (GB) | 2013-11-21 | — | — | US | disclosed |
| US-20130310411-A1 | NOVEL ACRIDINE DERIVATIVES | PHARMINOX LIMITED (GB) | 2013-11-21 | — | — | US | disclosed |
| EP-2621929-A1 | NOVEL ACRIDINE DERIVATIVES | Pharminox Limited (GB) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012042265-A1 | NOVEL ACRIDINE DERIVATIVES | PHARMINOX LIMITED (GB) | 2012-04-05 | — | — | WO | disclosed |
| WO-2012042265-A1 | NOVEL ACRIDINE DERIVATIVES | PHARMINOX LIMITED (GB) | 2012-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130310411-A1 | NOVEL ACRIDINE DERIVATIVES | TERT, NAT10, POT1 | ENPP3 436/4885ENPP1 117/4885MEN1 2652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.