Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14126140 | 0.93 | KDM4E (0.62) | KDM4EPHLPP2ADORA2ACYP19A1KMT2A | |
| SCHEMBL30603139 | 0.92 | KDM4E (0.68) | KDM4EPHLPP2ADORA2ACYP19A1KMT2A | |
| SCHEMBL31038657 | 0.92 | KDM4E (0.68) | KDM4EPHLPP2ADORA2ACYP19A1KMT2A | |
| SCHEMBL2448633 | 0.92 | KDM4E (0.68) | KDM4EPHLPP2ADORA2ACYP19A1KMT2A | |
| SCHEMBL4540441 | 0.87 | APP (0.58) | KDM4EPHLPP2ADORA2ACYP19A1KMT2A | |
| SCHEMBL20535915 | 0.87 | KDM4E (0.62) | KDM4EPHLPP2ADORA2ACYP19A1KMT2A | |
| SCHEMBL31500228 | 0.86 | KDM4E (0.61) | KDM4EPHLPP2ADORA2ACYP19A1KMT2A | |
| SCHEMBL9594726 | 0.86 | KDM4E (0.57) | KDM4EPHLPP2ADORA2ACYP19A1KMT2A | |
| SCHEMBL9594325 | 0.85 | MPO (0.48) | KDM4EKMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL6023624 | 0.85 | KDM4E (0.61) | KDM4EKMT2AMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012164484-A1 | ADENOSINE OR DEOXYADENOSINE DERIVATIVES MODIFIED AT POSITION 8 AND A METHOD OF SYNTHESIS THEREOF | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 2012-12-06 | — | — | WO | disclosed |
| US-4394487-A | GRAFTING AFFINE RESIDUE FOR NUCLEIC ACIDS ONTO POLYMERIC CARRIER | BOEHRINGER MANNHEIM GMBH (DE) | 1983-07-19 | — | — | US | disclosed |
| US-4335226-A | Adsorbent for the affinity-specific separation of macromolecular materials | BOEHRINGER MANNHEIM GMBH (DE) | 1982-06-15 | — | — | US | disclosed |