Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 4/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL8681495 | 0.96 | MAPT (0.46) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9017142 | 0.80 | ALDH1A1 (0.47) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8682666 | 0.79 | MAPT (0.56) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| Water SCHEMBL8681365 | 0.79 | ALDH1A1 (0.46) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| Sulfuric Acid SCHEMBL8681489 | 0.77 | CA1 (0.45) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| Sulfuric Acid SCHEMBL8681496 | 0.76 | CA1 (0.44) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8686302 | 0.71 | MAPK8 (0.57) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9017131 | 0.71 | MAPK1 (0.41) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| Water SCHEMBL8681442 | 0.70 | MAPK1 (0.41) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| Sulfuric Acid SCHEMBL8681538 | 0.68 | MAPK1 (0.39) | MAPTMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572635-B1 | COMPOUNDS HAVING A GUANIDINE STRUCTURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | CENTRE NAT RECH SCIENT (FR) | 1996-12-27 | — | — | EP | disclosed |
| WO-1993010102-A1 | NOVEL COMPOUNDS HAVING A GUANIDINE STRUCTURE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) | 1993-05-27 | — | — | WO | disclosed |