Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TPH1 | P17752 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL8681365 | 0.99 | ALDH1A1 (0.46) | ALDH1A1ACHEBCHEMAPTKDM4E | |
| Sulfuric Acid SCHEMBL8681489 | 0.96 | CA1 (0.45) | ALDH1A1ACHEBCHEMAPTKDM4E | |
| Sulfuric Acid SCHEMBL8681496 | 0.95 | CA1 (0.44) | ALDH1A1ACHEBCHEMAPTKDM4E | |
| SCHEMBL8682662 | 0.82 | ALDH1A1 (0.55) | ALDH1A1ACHEBCHEMAPTKDM4E | |
| SCHEMBL9017147 | 0.80 | MAPT (0.49) | ALDH1A1MAPTKDM4EGAAMEN1 | |
| Sulfuric Acid SCHEMBL8681495 | 0.77 | MAPT (0.46) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8686297 | 0.74 | L3MBTL1 (0.55) | ALDH1A1ACHEBCHEKDM4ECA1 | |
| SCHEMBL8686290 | 0.69 | ALDH1A1 (0.54) | ALDH1A1ACHEMAPTKDM4EGAA | |
| SCHEMBL9017131 | 0.68 | MAPK1 (0.41) | ALDH1A1ACHEMAPTKDM4ECA1 | |
| SCHEMBL10397458 | 0.68 | MAPT (0.64) | ALDH1A1MAPTCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572635-B1 | COMPOUNDS HAVING A GUANIDINE STRUCTURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | CENTRE NAT RECH SCIENT (FR) | 1996-12-27 | — | — | EP | disclosed |
| WO-1993010102-A1 | NOVEL COMPOUNDS HAVING A GUANIDINE STRUCTURE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) | 1993-05-27 | — | — | WO | disclosed |