Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.56 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.39 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13222885 | 0.90 | LMNA (0.49) | LMNANAPRTP4HTML3MBTL1KDM4E | |
| SCHEMBL12129562 | 0.84 | KDM4E (0.58) | LMNAP4HTML3MBTL1KDM4EALOX15 | |
| SCHEMBL7110101 | 0.81 | KDM4E (0.57) | LMNANAPRTP4HTML3MBTL1KDM4E | |
| Dipicolinic Acid SCHEMBL3262108 | 0.78 | LMNA (0.83) | LMNANAPRTP4HTML3MBTL1KDM4E | |
| SCHEMBL4811257 | 0.77 | LMNA (0.62) | LMNANAPRTP4HTML3MBTL1KDM4E | |
| SCHEMBL409030 | 0.75 | KDM4E (0.55) | LMNAP4HTML3MBTL1KDM4EALOX15 | |
| SCHEMBL11541004 | 0.74 | P4HTM (0.55) | LMNANAPRTP4HTML3MBTL1KDM4E | |
| SCHEMBL15940538 | 0.74 | KDM4E (0.57) | LMNANAPRTP4HTML3MBTL1KDM4E | |
| SCHEMBL16555707 | 0.74 | LMNA (0.68) | LMNANAPRTP4HTML3MBTL1KDM4E | |
| 2-Picolinic Acid SCHEMBL674837 | 0.73 | LMNA (1.00) | LMNANAPRTP4HTML3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537816-B1 | Herbicidal picolinamide derivatives | SHELL INT RESEARCH (NL) | 1996-04-24 | — | — | EP | disclosed |
| US-5371061-A | Herbicidal picolinamide derivatives | AMERICAN CYANAMID COMPANY (US) | 1994-12-06 | — | — | US | disclosed |
| EP-0537816-A1 | Herbicidal picolinamide derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-04-21 | — | — | EP | disclosed |