SCHEMBL4811257

SCHEMBL4811257

O=C(O)c1cccc(-c2ccccn2)n1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.62
L3MBTL1 Q9Y468 3/20 0.62
P4HTM Q9NXG6 2/20 0.62
NAPRT Q6XQN6 1/20 0.62
KDM4E B2RXH2 10/20 0.61
ALOX15 P16050 3/20 0.61
TDP1 Q9NUW8 3/20 0.61
CCR1 P32246 2/20 0.61
CCR5 P51681 2/20 0.61
CCR8 P51685 2/20 0.61
TP53 P04637 2/20 0.61
HTT P42858 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
ALPL P05186 1/20 0.61
HSP90AA1 P07900 1/20 0.61
ALPI P09923 1/20 0.61
ALPG P10696 1/20 0.61
MAPK1 P28482 1/20 0.61
TSHR P16473 1/20 0.57
ACMSD Q8TDX5 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1456823 0.93 KDM4E (0.58) LMNAL3MBTL1P4HTMNAPRTKDM4E
SCHEMBL20401669 0.88 L3MBTL1 (0.49) LMNAL3MBTL1P4HTMNAPRTKDM4E
SCHEMBL29357675 0.86 KDM4E (0.76) LMNAL3MBTL1P4HTMNAPRTKDM4E
SCHEMBL70765 0.86 KDM4E (0.76) LMNAL3MBTL1P4HTMNAPRTKDM4E
SCHEMBL17489130 0.86 LMNA (0.50) LMNAL3MBTL1P4HTMNAPRTKDM4E
SCHEMBL20412771 0.86 KMT2A (0.68) LMNAL3MBTL1P4HTMNAPRTKDM4E
SCHEMBL29355234 0.84 KDM4E (0.73) LMNAL3MBTL1P4HTMNAPRTKDM4E
SCHEMBL143651 0.84 KDM4E (0.73) LMNAL3MBTL1P4HTMNAPRTKDM4E
SCHEMBL935065 0.84 KDM4E (0.59) LMNAL3MBTL1P4HTMNAPRTKDM4E
SCHEMBL3165743 0.84 ALDH1A1 (0.63) LMNAL3MBTL1P4HTMNAPRTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250362307-A1 PHOTOACTIVE ANTIBODY CONJUGATE LIAO JUNG CHI (TW) 2025-11-27 US claimed
EP-4473309-A1 PHOTOACTIVE ANTIBODY CONJUGATE Syncell (Taiwan) Inc. (TW) 2024-12-11 EP claimed
CN-117142938-A Method for preparing 1, 4-naphthoquinone compound by selectively oxidizing aromatic ketone 大连理工大学 2023-12-01 CN claimed
CN-117026295-A COF composite material and preparation method and application thereof 深圳技术大学 2023-11-10 CN claimed
WO-2023196986-A1 PHOTOACTIVE ANTIBODY CONJUGATE Syncell (Taiwan) Inc. (TW) 2023-10-12 WO claimed
CN-113559939-B Alpha alkylation reaction catalyst of nitrile and preparation method thereof 郑州大学 2023-06-23 CN claimed
CN-113559939-A Alpha alkylation reaction catalyst for nitrile and preparation method thereof 郑州大学 2021-10-29 CN claimed
CN-111440174-B Pyridine amide compound and preparation method and application thereof 广州医科大学 2021-07-09 CN claimed
CN-109970814-A Pincerlike ruthenium compound of the asymmetric NNN ' containing pyridine-pyridine-imidazoline and preparation method thereof 郑州大学 2019-07-05 CN claimed
US-20250362307-A1 PHOTOACTIVE ANTIBODY CONJUGATE LIAO JUNG CHI (TW) 2025-11-27 US disclosed
EP-4473309-A1 PHOTOACTIVE ANTIBODY CONJUGATE Syncell (Taiwan) Inc. (TW) 2024-12-11 EP disclosed
CN-118029974-A Steam injection catalytic modification coking sand prevention method and catalyst for loose sandstone heavy oil reservoir 中国石油化工股份有限公司 2024-05-14 CN disclosed
CN-117751124-A Spiro oxindole compounds and application thereof in preparing antiviral protease inhibitor medicines 南京药石科技股份有限公司 2024-03-22 CN disclosed
CN-117377668-A Inhalant formulations of PGDH inhibitors and methods of use thereof 迈欧伏特治疗公司 2024-01-09 CN disclosed
CN-101223141-A Certain substituted amides, method of making, and method of use thereof CGI PHARMACEUTICALS INC (US) 2008-07-16 CN disclosed
EP-1742936-A2 POLYCYCLIC PYRIDINES AS POTASSIUM ION CHANNEL MODULATORS Icagen, Inc. (US) 2007-01-17 EP disclosed
EP-1644372-A2 SUBSTITUTED QUINOLIN-4-YLAMINE ANALOGUES NEUROGEN CORPORATION (US) 2006-04-12 EP disclosed
WO-2005100340-A2 POLYCYCLIC PYRIDINES AS POTASSIUM ION CHANNEL MODULATORS ICAGEN, INC. (US) 2005-10-27 WO disclosed
US-20050227958-A1 Polycyclic pyridines as potassium ion channel modulators ICAGEN, INC. (US) 2005-10-13 US disclosed
WO-2005007652-A2 SUBSTITUTED QUINOLIN-4-YLAMINE ANALOGUES NEUROGEN CORPORATION (US) 2005-01-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050227958-A1 Polycyclic pyridines as potassium ion channel modulators KCNJ2, KCNH2, KCNQ1 LMNA 3338/4885L3MBTL1 3704/4885P4HTM 624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.