Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | FTO | Q9C0B1 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | RECQL | P46063 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMAD3 | P84022 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15648378 | 0.91 | ALDH1A1 (0.55) | ALDH1A1HPGDBRCA1HSD17B10ALOX12 | |
| SCHEMBL134733 | 0.84 | ALDH1A1 (0.63) | ALDH1A1HPGDBRCA1HSD17B10ALOX12 | |
| SCHEMBL29361906 | 0.84 | ALDH1A1 (0.63) | ALDH1A1HPGDBRCA1HSD17B10ALOX12 | |
| SCHEMBL30887310 | 0.84 | ALDH1A1 (0.63) | ALDH1A1HPGDBRCA1HSD17B10ALOX12 | |
| SCHEMBL30887311 | 0.84 | ALDH1A1 (0.63) | ALDH1A1HPGDBRCA1HSD17B10ALOX12 | |
| SCHEMBL5453230 | 0.83 | ALDH1A1 (0.62) | ALDH1A1HPGDBRCA1HSD17B10ALOX12 | |
| SCHEMBL6726793 | 0.82 | ALDH1A1 (0.58) | ALDH1A1HPGDBRCA1HSD17B10ALOX12 | |
| SCHEMBL9068067 | 0.80 | ALDH1A1 (0.58) | ALDH1A1HPGDBRCA1HSD17B10ALOX12 | |
| SCHEMBL6637206 | 0.80 | ALDH1A1 (0.55) | ALDH1A1HPGDBRCA1HSD17B10ALOX12 | |
| SCHEMBL6884426 | 0.79 | ALDH1A1 (0.45) | ALDH1A1HPGDBRCA1HSD17B10ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160116448-A1 | pH-MODULATED QUENCHERS OF FLUORESCENCE | BERRY AND ASSOCIATES, INC. | 2016-04-28 | — | — | US | disclosed |
| US-5489507-A | SIMULTANEOUS AMPLIFICATION OF TARGET DNA AND DYE-LABELED ALLELIC DNA; FORMING MATCHED DUPLEXES; ILLUMINATION; MEDICAL DIAGNOSIS | PERKIN-ELMER CORPORATION (US) | 1996-02-06 | — | — | US | disclosed |
| EP-0233053-B1 | Method of detecting electrophoretically separated oligonucleotides | APPLIED BIOSYSTEMS (US) | 1994-06-01 | — | — | EP | disclosed |
| US-4855225-A | LABELING WITH FLUORESCENT OR RHODANINE DYES | APPLIED BIOSYSTEMS, INC. (US) | 1989-08-08 | — | — | US | disclosed |
| EP-0233053-A2 | Method of detecting electrophoretically separated oligonucleotides | APPLIED BIOSYSTEMS, INC. (US) | 1987-08-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160116448-A1 | pH-MODULATED QUENCHERS OF FLUORESCENCE | NHERF1, ANXA5, ARFGEF1 | ALDH1A1 323/4885HPGD 838/4885BRCA1 1071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.