Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11420023 | 0.85 | CYP19A1 (0.44) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL9017220 | 0.82 | PNMT (0.45) | TDP1TSHRALDH1A1LMNAMEN1 | |
| Acenaphthene SCHEMBL8740457 | 0.81 | ALDH1A1 (0.57) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL5574402 | 0.78 | TSHR (0.50) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL29903867 | 0.77 | TSHR (0.58) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL10788183 | 0.77 | TSHR (0.58) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| Acenaphthene SCHEMBL28242769 | 0.76 | ALDH1A1 (0.50) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL9404200 | 0.74 | TDP1 (0.50) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL1826053 | 0.73 | TDP1 (0.62) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL30738237 | 0.73 | TDP1 (0.62) | TDP1TSHRALDH1A1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107141257-A | A kind of naphthalimide polyamines conjugate containing terminal substituent and its preparation method and application | 河南大学 | 2017-09-08 | — | — | CN | disclosed |
| CN-103948595-B | Acid imide position or 4-position substituted 1,8-naphthalimide derivative is as the purposes of PARP inhibitor | 华侨大学 | 2017-01-04 | — | — | CN | disclosed |
| CN-103948595-A | Use of imide site or 4-substituted 1, 8-naphthyl imide derivatives as PARP (poly adeno-sine diphosphate ribose polymerase) inhibitors | UNIV HUAQIAO | 2014-07-30 | — | — | CN | disclosed |
| US-20070248911-A1 | Pattern forming method and bilayer film | IWASAWA HARUO | 2007-10-25 | — | — | US | disclosed |
| US-7244549-B2 | Pattern forming method and bilayer film | JSR CORPORATION (JP) | 2007-07-17 | — | — | US | disclosed |
| US-20030073040-A1 | Pattern forming method and bilayer film | JSR CORPORATION (JP) | 2003-04-17 | — | — | US | disclosed |
| US-4413091-A | POLYVINYL ACETALS BY HYDROLYSIS OF POLYVINYL ALCOHOL, REACTION WITH AN ACYCLIC ALDEHYDE AND AN AZIDE ARYL ALDEHYDE | TOKYO OHKA KOGYO KABUSHIKI KAISHA (JP) | 1983-11-01 | — | — | US | disclosed |
| US-4226928-A | PHTHALOCYANINE LAYER, AROMATIC NITRO COMPOUND, POLYVINYLCARBAZOLE PHOTOCONDUCTOR | MITA INDUSTRIAL COMPANY, LTD. (JP) | 1980-10-07 | — | — | US | disclosed |
| US-4214907-A | Photosensitive material for electrophotography having a polyvinyl carbazole derivative, phthalocyanine, and an electron-acceptor | MITA INDUSTRIAL COMPANY, LTD. (JP) | 1980-07-29 | — | — | US | disclosed |
| US-4212813-A | OXIDIZING ACENAPHTHENES, COBALT COMPOUND CATALYST | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1980-07-15 | — | — | US | disclosed |
| US-3969323-A | Photo-crosslinkable 2-pyrone polymers and processes for the manufacture thereof | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-07-13 | — | — | US | disclosed |