Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.63 |
| ▸ | DRD3 | P35462 | 6/20 | 0.63 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017303 | 0.86 | DRD2 (0.67) | DRD2DRD3MTNR1AMTNR1BCA1 | |
| SCHEMBL8414285 | 0.82 | MTNR1A (0.46) | DRD2DRD3MTNR1AMTNR1BCA1 | |
| SCHEMBL8414321 | 0.81 | MTNR1A (0.45) | DRD2DRD3MTNR1AMTNR1BCA1 | |
| SCHEMBL8812817 | 0.80 | PTGIR (0.46) | DRD2DRD3MTNR1AMTNR1BCA1 | |
| SCHEMBL29429678 | 0.78 | DRD2 (1.00) | DRD2DRD3MTNR1AMTNR1BPLAU | |
| SCHEMBL43366 | 0.78 | DRD2 (1.00) | DRD2DRD3MTNR1AMTNR1BPLAU | |
| SCHEMBL895845 | 0.78 | DRD2 (1.00) | DRD2DRD3MTNR1AMTNR1BPLAU | |
| SCHEMBL895742 | 0.78 | DRD2 (1.00) | DRD2DRD3MTNR1AMTNR1BPLAU | |
| SCHEMBL29547385 | 0.78 | DRD2 (1.00) | DRD2DRD3MTNR1AMTNR1BPLAU | |
| SCHEMBL8811674 | 0.77 | PTGIR (0.46) | MTNR1AMTNR1BCA1CA2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749424-A1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | EP | disclosed |