Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 15/20 | 0.50 |
| ▸ | DRD3 | P35462 | 8/20 | 0.50 |
| ▸ | DRD4 | P21917 | 6/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10043010 | 0.78 | DRD2 (0.57) | DRD2DRD3DRD4CHRM2CHRM1 | |
| SCHEMBL3318329 | 0.78 | DRD2 (0.57) | DRD2DRD3DRD4CHRM2CHRM1 | |
| SCHEMBL7776659 | 0.71 | CHRM2 (0.58) | DRD2DRD3DRD4CHRM2CHRM1 | |
| SCHEMBL9017272 | 0.69 | DRD2 (0.58) | DRD2DRD3DRD4CHRM2CHRM1 | |
| SCHEMBL8483378 | 0.68 | MTNR1A (0.62) | DRD2DRD3DRD4CHRM2CHRM1 | |
| SCHEMBL8483383 | 0.68 | MTNR1A (0.62) | DRD2DRD3DRD4CHRM2CHRM1 | |
| SCHEMBL29062558 | 0.68 | CYP19A1 (0.62) | DRD2DRD3DRD4CHRM2CHRM1 | |
| SCHEMBL10644420 | 0.67 | DRD2 (0.82) | DRD2DRD3DRD4 | |
| SCHEMBL21798816 | 0.67 | DRD2 (0.77) | DRD2DRD3DRD4 | |
| SCHEMBL5985767 | 0.67 | CA2 (0.43) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749424-A1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | EP | disclosed |