SCHEMBL9017375

SCHEMBL9017375

CCCCCCCCCCCCCCCCS(=O)(=O)c1ccc(NN)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.49
THRA P10827 1/20 0.49
CA2 P00918 9/20 0.47
CA1 P00915 5/20 0.47
CA12 O43570 4/20 0.47
CA9 Q16790 4/20 0.47
CA4 P22748 1/20 0.47
CA6 P23280 1/20 0.47
CA5A P35218 1/20 0.47
CA7 P43166 1/20 0.47
CA14 Q9ULX7 1/20 0.47
CA5B Q9Y2D0 1/20 0.47
ALDH1A1 P00352 4/20 0.46
MAPT P10636 3/20 0.46
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
MCHR1 Q99705 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9704339 0.93 CA2 (0.50) THRBTHRACA2CA1CA12
SCHEMBL9303466 0.89 THRB (0.41) THRBTHRACA2CA1CA12
SCHEMBL11131722 0.81 GAA (0.60) THRBTHRACA2CA1CA12
SCHEMBL2123298 0.81 GAA (0.60) THRBTHRACA2CA1CA12
SCHEMBL22471791 0.81 GAA (0.60) THRBTHRACA2CA1CA12
SCHEMBL8878487 0.81 GAA (0.60) THRBTHRACA2CA1CA12
SCHEMBL11213098 0.81 GAA (0.60) THRBTHRACA2CA1CA12
SCHEMBL8158540 0.81 GAA (0.60) THRBTHRACA2CA1CA12
SCHEMBL8164968 0.81 ALDH1A1 (0.65) THRBTHRACA2CA1CA12
SCHEMBL10300267 0.80 THRB (0.55) THRBTHRACA2ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5500439-A FOOD PRESERVATIVE, DISCOLORATION INHIBITION FOR TEETH, GLYCOSYLATION INHIBITION ALTEON INC. (US) 1996-03-19 US disclosed
US-5109036-A With alkysulfonylphenylhydrazine accelerator; storage stability CECA, S.A. (FR) 1992-04-28 US disclosed
EP-0443916-A1 Anaerobically curing adhesive compositions CECA S.A. (FR) 1991-08-28 EP disclosed