Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.36 |
| ▸ | CNR1 | P21554 | 7/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017452 | 0.79 | CNR2 (0.41) | CNR2CNR1TRPV1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9017449 | 0.79 | HDAC1 (0.45) | CNR2CNR1TRPV1HDAC3HDAC1 | |
| SCHEMBL9017438 | 0.74 | KMT2A (0.36) | CNR2CNR1TRPV1 | |
| SCHEMBL23162447 | 0.73 | ALDH1A1 (0.42) | CNR2CNR1BACE1ALDH1A1KDM4E | |
| SCHEMBL21727711 | 0.69 | AKR1C3 (0.39) | CNR2CNR1TRPV1SMN1; SMN2KDM4E | |
| SCHEMBL25965182 | 0.67 | ALDH1A1 (0.39) | CNR2CNR1TRPV1ALDH1A1SMN1; SMN2 | |
| SCHEMBL23802246 | 0.66 | CNR2 (0.50) | CNR2CNR1TRPV1ALDH1A1 | |
| SCHEMBL23461353 | 0.66 | CNR2 (0.55) | CNR2CNR1TRPV1 | |
| SCHEMBL17129735 | 0.66 | ALDH1A1 (0.46) | CNR2CNR1TRPV1ALDH1A1KDM4E | |
| SCHEMBL23162732 | 0.65 | RXRA (0.42) | CNR2CNR1ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563292-A | TREATING HYPERPROLIFERATIVE SKIN DISEASE | SCHERING CORPORATION (US) | 1996-10-08 | — | — | US | disclosed |
| EP-0495917-A1 | LIPOXYGENASE INHIBITORS | SCHERING CORPORATION (US) | 1992-07-29 | — | — | EP | disclosed |
| WO-1991005757-A1 | LIPOXYGENASE INHIBITORS | SCHERING CORPORATION (US) | 1991-05-02 | — | — | WO | disclosed |