Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 11/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.45 |
| ▸ | CNR2 | P34972 | 8/20 | 0.44 |
| ▸ | CNR1 | P21554 | 7/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017440 | 0.79 | CNR2 (0.36) | HDAC1HDAC8HDAC3HDAC2CNR2 | |
| SCHEMBL9017452 | 0.78 | CNR2 (0.41) | CNR2CNR1TRPV1 | |
| SCHEMBL9017438 | 0.73 | KMT2A (0.36) | CNR2CNR1TRPV1 | |
| SCHEMBL23198361 | 0.70 | CNR2 (0.50) | CNR2CNR1TRPV1 | |
| SCHEMBL23461353 | 0.68 | CNR2 (0.55) | CNR2CNR1TRPV1 | |
| SCHEMBL23802179 | 0.67 | CNR2 (0.57) | CNR2CNR1TRPV1 | |
| SCHEMBL11422604 | 0.67 | HDAC1 (0.56) | HDAC1HDAC6HDAC8HDAC4HDAC3 | |
| SCHEMBL21727711 | 0.65 | AKR1C3 (0.39) | CNR2CNR1TRPV1 | |
| SCHEMBL15506135 | 0.65 | ALDH1A1 (0.50) | CNR2CNR1 | |
| SCHEMBL23162732 | 0.65 | RXRA (0.42) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563292-A | TREATING HYPERPROLIFERATIVE SKIN DISEASE | SCHERING CORPORATION (US) | 1996-10-08 | — | — | US | disclosed |
| WO-1991005757-A1 | LIPOXYGENASE INHIBITORS | SCHERING CORPORATION (US) | 1991-05-02 | — | — | WO | disclosed |