Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | AGXT | P21549 | 3/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | CALM1 | P0DP23 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4976688 | 0.94 | CYP19A1 (0.48) | CYP19A1PTGS2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8056115 | 0.82 | CYP19A1 (0.41) | CYP19A1PTGS2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL30380963 | 0.81 | CYP19A1 (0.56) | CYP19A1PTGS2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL20098971 | 0.81 | CYP19A1 (0.56) | CYP19A1PTGS2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL5832074 | 0.80 | CYP19A1 (0.50) | CYP19A1PTGS2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL29738341 | 0.80 | CYP19A1 (0.50) | CYP19A1PTGS2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8281936 | 0.80 | ALDH1A1 (0.35) | CYP19A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL31052 | 0.80 | ALDH1A1 (0.58) | CYP19A1PTGS2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL2130249 | 0.80 | ALDH1A1 (0.35) | CYP19A1ALDH1A1IDO1MAPK1TDP1 | |
| SCHEMBL5318702 | 0.79 | MAPT (0.47) | CYP19A1PTGS2ALDH1A1HTR6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5538847-A | Chemiluminescent 1,2-dioxetanes | TROPIX, INC. (US) | 1996-07-23 | — | — | US | disclosed |
| EP-0649417-A1 | IMPROVED CHEMILUMINESCENT 1,2-DIOXETANES | TROPIX, INC. (US) | 1995-04-26 | — | — | EP | disclosed |
| EP-0649417-A4 | IMPROVED CHEMILUMINESCENT 1,2-DIOXETANES. | TROPIX INC (US) | 1995-02-27 | — | — | EP | disclosed |
| WO-1994026726-A1 | IMPROVED CHEMILUMINESCENT 1,2-DIOXETANES | TROPIX, INC. (US) | 1994-11-24 | — | — | WO | disclosed |