Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.40 |
| ▸ | DRD3 | P35462 | 5/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | PNMT | P11086 | 6/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7387150 | 0.76 | CYP19A1 (0.47) | DRD2DRD3CYP19A1PNMTMCHR1 | |
| SCHEMBL11211912 | 0.74 | DRD2 (0.46) | DRD2DRD3CYP19A1PNMTMCHR1 | |
| SCHEMBL11210812 | 0.71 | CYP3A4 (0.51) | DRD2DRD3CYP19A1PNMTMCHR1 | |
| SCHEMBL22070979 | 0.71 | PNMT (0.45) | DRD2DRD3CYP19A1PNMTMCHR1 | |
| SCHEMBL11215164 | 0.70 | CYP3A4 (0.53) | DRD2DRD3CYP19A1PNMTMCHR1 | |
| SCHEMBL1725458 | 0.69 | DRD2 (0.50) | DRD2DRD3PNMTHTR1DHTR1B | |
| SCHEMBL2724775 | 0.68 | OPRK1 (0.57) | DRD2DRD3 | |
| SCHEMBL2722643 | 0.68 | OPRK1 (0.57) | DRD2DRD3 | |
| SCHEMBL14525540 | 0.68 | DRD2 (0.49) | DRD2DRD3PNMTCYP11B2 | |
| SCHEMBL11137820 | 0.67 | MCHR1 (0.52) | CYP19A1MCHR1DGAT1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576343-A | ANTICOAGULANTS; BLOOD-COAGULATION FACTOR X INHIBITORS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |