SCHEMBL9017703

SCHEMBL9017703

Cc1cn([C@H]2C[C@H](OCc3ccccc3-c3ccccc3)[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.78

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.69
TK1 P04183 5/20 0.58
TK2 O00142 3/20 0.58
LMNA P02545 2/20 0.52
TSHR P16473 2/20 0.52
ALB P02768 1/20 0.52
PKM P14618 1/20 0.52
BLM P54132 1/20 0.52
PMP22 Q01453 1/20 0.52
CYP2D6 P10635 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9017662 0.88 RNASE1 (0.68) RNASE1TK1TK2ALBPKM
SCHEMBL31355237 0.88 RNASE1 (0.72) RNASE1TK1TK2
SCHEMBL21563859 0.85 RNASE1 (0.61) RNASE1TK1TK2LMNATSHR
SCHEMBL21545799 0.85 RNASE1 (0.61) RNASE1TK1TK2LMNATSHR
SCHEMBL8659687 0.84 TYMS (0.61) RNASE1TK1
SCHEMBL8659684 0.84 TYMS (0.61) RNASE1TK1
SCHEMBL9100746 0.83 LMNA (0.60) RNASE1TK1TK2LMNATSHR
SCHEMBL1334035 0.83 RNASE1 (0.71) RNASE1TK1TK2LMNATSHR
SCHEMBL16704351 0.83 RNASE1 (0.71) RNASE1TK1TK2LMNATSHR
SCHEMBL1334032 0.83 RNASE1 (0.71) RNASE1TK1TK2LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0611075-B1 Modified oligodeoxyribonucleotides, their preparation and their therapeutic use SANKYO CO (JP) 1996-12-18 EP disclosed
CN-1098107-A modified oligodeoxynucleotides, their preparation and their therapeutic use SANKYO CO (JP) 1995-02-01 CN disclosed
EP-0611075-A1 Modified oligodeoxyribonucleotides, their preparation and their therapeutic use SANKYO COMPANY LIMITED (JP) 1994-08-17 EP disclosed