Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 5/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | CTSB | P07858 | 2/20 | 0.34 |
| ▸ | CTSH | P09668 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6882280 | 0.94 | CYSLTR2 (0.43) | CYSLTR2CYSLTR1CNR2ALDH1A1TDP1 | |
| SCHEMBL1880780 | 0.86 | CYSLTR2 (0.40) | CYSLTR2CYSLTR1CNR2CTSKCTSL | |
| SCHEMBL5360505 | 0.83 | CYSLTR2 (0.35) | CYSLTR2CYSLTR1CNR2KMT2APOLB | |
| SCHEMBL1332960 | 0.81 | CYSLTR2 (0.45) | CYSLTR2CYSLTR1KMT2AALDH1A1MEN1 | |
| SCHEMBL2284723 | 0.79 | CYSLTR2 (0.39) | CYSLTR2CYSLTR1CNR2KMT2AALDH1A1 | |
| SCHEMBL6682051 | 0.79 | MEN1 (0.40) | CYSLTR2CYSLTR1CNR2CTSKCTSL | |
| SCHEMBL8082979 | 0.77 | PPARG (0.45) | CYSLTR2CYSLTR1CNR2KMT2AALDH1A1 | |
| SCHEMBL15054438 | 0.77 | CYSLTR2 (0.40) | CYSLTR2CYSLTR1CNR2CTSKCTSL | |
| SCHEMBL490156 | 0.76 | ALDH1A1 (0.40) | CYSLTR2CYSLTR1KMT2AALDH1A1KDM4E | |
| SCHEMBL9857565 | 0.75 | CYSLTR2 (0.40) | CYSLTR2CYSLTR1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529870-B1 | Preparation of 2-hydroxyarylaldehydes | ZENECA LTD (GB) | 1996-01-17 | — | — | EP | disclosed |
| US-5260487-A | Process for the preparation of 2-hydroxyarylaldehydes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-11-09 | — | — | US | disclosed |
| EP-0529870-A2 | Preparation of 2-hydroxyarylaldehydes | ZENECA LIMITED (GB) | 1993-03-03 | — | — | EP | disclosed |