SCHEMBL1880780

SCHEMBL1880780

CCCCC(CCC)c1ccccc1C=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 3/20 0.40
CYSLTR1 Q9Y271 3/20 0.40
MEN1 O00255 1/20 0.39
LMNA P02545 1/20 0.39
THRB P10828 1/20 0.39
BLM P54132 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 2/20 0.37
TSHR P16473 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.34
HPGD P15428 1/20 0.34
HTT P42858 1/20 0.34
CTSK P43235 4/20 0.33
TRIM24 O15164 1/20 0.33
TRIM33 Q9UPN9 1/20 0.33
GBA1 P04062 1/20 0.33
CTSL P07711 2/20 0.33
CTSB P07858 2/20 0.33
CTSH P09668 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1332960 0.94 CYSLTR2 (0.45) CYSLTR2CYSLTR1MEN1LMNATHRB
SCHEMBL9017707 0.86 CYSLTR2 (0.39) CYSLTR2CYSLTR1MEN1LMNATHRB
SCHEMBL6682051 0.81 MEN1 (0.40) CYSLTR2CYSLTR1MEN1LMNATHRB
SCHEMBL6882280 0.81 CYSLTR2 (0.43) CYSLTR2CYSLTR1TDP1ALDH1A1CNR2
SCHEMBL9857565 0.81 CYSLTR2 (0.40) CYSLTR2CYSLTR1MEN1LMNATHRB
SCHEMBL6240407 0.80 MEN1 (0.39) CYSLTR2CYSLTR1MEN1LMNATHRB
SCHEMBL15054438 0.80 CYSLTR2 (0.40) CYSLTR2CYSLTR1MEN1KMT2AALDH1A1
SCHEMBL490156 0.79 ALDH1A1 (0.40) CYSLTR2CYSLTR1KMT2AALDH1A1
SCHEMBL10586358 0.79 CYSLTR2 (0.44) CYSLTR2CYSLTR1MEN1KMT2AALDH1A1
SCHEMBL8741674 0.79 CYSLTR2 (0.40) CYSLTR2CYSLTR1ALDH1A1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122071473-A Application of organic compound in photostable field effect transistor, photostable field effect transistor and electronic device 中国石油化工股份有限公司 2026-05-22 CN disclosed
CN-120004747-A Synthesis method of fingolimod hydrochloride 杭州科耀医药科技有限公司 2025-05-16 CN disclosed
CN-119285536-A Fluorescent probe and application thereof 华中科技大学鄂州工业技术研究院 2025-01-10 CN disclosed
US-11629220-B2 Renewable furan based amine curing agents for epoxy thermoset Drexel Unversity (US) 2023-04-18 US disclosed
CN-108069956-B 1-azabicyclo [2,2,2] oct-4-yl phenyl ketone compound, preparation method and application thereof 扬州奥锐特药业有限公司 2021-03-16 CN disclosed
EP-3672947-A1 RENEWABLE FURAN BASED AMINE CURING AGENTS FOR EPOXY THERMOSET The United States of America as represented by the Secretary of the Army (US) 2020-07-01 EP disclosed
US-20200172658-A1 RENEWABLE FURAN BASED AMINE CURING AGENTS FOR EPOXY THERMOSET DREXEL UNIVERSITY (US) 2020-06-04 US disclosed
WO-2019040389-A1 RENEWABLE FURAN BASED AMINE CURING AGENTS FOR EPOXY THERMOSET PALMESE GIUSEPPE R (US) 2019-02-28 WO disclosed
US-20110106241-A1 COMPOSITIONS AND METHODS FOR INHIBITING SPHINGOSINE KINASE UNIVERSITY OF VIRGINIA PATENT FOUNDATION 2011-05-05 US disclosed
WO-2009146112-A1 COMPOSITIONS AND METHODS FOR INHIBITING SPHINGOSINE KINASE UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2009-12-03 WO disclosed
US-6165234-A FOR IMPARTING REVERSIBLE COLOR CHANGES TO WAXES AND CANDLES WHEN HEATED OR WHEN WAX MELTS OR WHEN THE CANDLE BURNS KANAKKANATT SEBASTIAN V (US) 2000-12-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110106241-A1 COMPOSITIONS AND METHODS FOR INHIBITING SPHINGOSINE KINASE SPHK2, SPHK1, S1PR2 CYSLTR2 931/4885CYSLTR1 1274/4885MEN1 1442/4885
US-20200172658-A1 RENEWABLE FURAN BASED AMINE CURING AGENTS FOR EPOXY THERMOSET EPHX2, AOC1, EPHX1 CYSLTR2 739/4885CYSLTR1 937/4885MEN1 3141/4885
US-11629220-B2 Renewable furan based amine curing agents for epoxy thermoset EPHX2, AOC1, EPHX1 CYSLTR2 739/4885CYSLTR1 937/4885MEN1 3141/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.