Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850477 | 0.88 | PTGS2 (0.46) | TLR8PTGS2MAPTCNR2SOAT1 | |
| SCHEMBL2607673 | 0.84 | TLR8 (0.50) | TLR8PTGS2NPC1RAB9AMAPT | |
| SCHEMBL348041 | 0.83 | PTGS2 (0.50) | TLR8PTGS2NPC1RAB9AMAPT | |
| SCHEMBL6835641 | 0.82 | PTGS2 (0.41) | TLR8PTGS2RAB9AMAPTALDH1A1 | |
| SCHEMBL9519759 | 0.79 | TLR8 (0.49) | TLR8PTGS2NPC1RAB9AMAPT | |
| SCHEMBL16519472 | 0.79 | PTGS2 (0.51) | TLR8PTGS2NPC1RAB9AMAPT | |
| SCHEMBL30417186 | 0.79 | PTGS2 (0.49) | TLR8PTGS2MAPTNPSR1ALDH1A1 | |
| SCHEMBL18758015 | 0.79 | PTGS2 (0.49) | TLR8PTGS2MAPTNPSR1ALDH1A1 | |
| SCHEMBL8007364 | 0.78 | MEN1 (0.53) | TLR8PTGS2NPC1RAB9AMAPT | |
| SCHEMBL25738323 | 0.77 | PTGS2 (0.50) | TLR8PTGS2NPC1RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5501821-A | OPTICAL ARTICLES FOR TRANSMISSION OF ELECTROMAGNETIC WAVES WITH DIPOLES | EASTMAN KODAK COMPANY (US) | 1996-03-26 | — | — | US | disclosed |