SCHEMBL348041

SCHEMBL348041

CCCCSc1cccc2c(SCCCC)cccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 7/20 0.50
MAPT P10636 3/20 0.45
NPSR1 Q6W5P4 3/20 0.45
ALDH1A1 P00352 2/20 0.45
TLR8 Q9NR97 1/20 0.44
LMNA P02545 2/20 0.41
HTT P42858 1/20 0.41
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MEN1 O00255 1/20 0.39
CNR2 P34972 1/20 0.39
KMT2A Q03164 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
S100A4 P26447 1/20 0.39
SOAT1 P35610 1/20 0.39
CYSLTR2 Q9NS75 1/20 0.38
CYSLTR1 Q9Y271 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16519472 0.96 PTGS2 (0.51) PTGS2MAPTNPSR1ALDH1A1TLR8
SCHEMBL2607673 0.88 TLR8 (0.50) PTGS2MAPTNPSR1ALDH1A1TLR8
SCHEMBL12405310 0.88 PTGS2 (0.45) PTGS2MAPTNPSR1ALDH1A1TLR8
SCHEMBL8672850 0.84 PTGS2 (0.59) PTGS2MAPTNPSR1ALDH1A1TLR8
SCHEMBL9017764 0.83 TLR8 (0.49) PTGS2MAPTNPSR1ALDH1A1TLR8
SCHEMBL18758015 0.83 PTGS2 (0.49) PTGS2MAPTNPSR1ALDH1A1TLR8
SCHEMBL14559232 0.83 PTGS2 (0.44) PTGS2MAPTNPSR1ALDH1A1TLR8
SCHEMBL30417186 0.83 PTGS2 (0.49) PTGS2MAPTNPSR1ALDH1A1TLR8
SCHEMBL200258 0.83 PTGS2 (0.54) PTGS2MAPTNPSR1ALDH1A1TLR8
SCHEMBL5316461 0.81 PTGS2 (0.50) PTGS2NPSR1ALDH1A1TLR8LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11335861-B2 Organic photoelectric conversion element SONY CORPORATION (JP) 2022-05-17 US disclosed
US-20200168815-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT SONY CORPORATION (JP) 2020-05-28 US disclosed
US-20120016147-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-19 US disclosed
US-8048982-B2 Method for producing aromatic compound polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-01 US disclosed
EP-2241548-A1 Vanadium di-nuclear complex Sumitomo Chemical Company, Limited (JP) 2010-10-20 EP disclosed
EP-2241547-A1 Method for producing aromatic compound polymer Sumitomo Chemical Company, Limited (JP) 2010-10-20 EP disclosed
US-20090018309-A1 Method for Producing Aromatic Compound Polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-15 US disclosed
EP-1767560-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER Sumitomo Chemical Company, Limited (JP) 2007-03-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090018309-A1 Method for Producing Aromatic Compound Polymer PAH, MAOA, AHR PTGS2 862/4885MAPT 2617/4885NPSR1 4251/4885
US-20200168815-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT CCNE2, GPX4, PPOX PTGS2 1554/4885MAPT 4514/4885NPSR1 2705/4885
US-11335861-B2 Organic photoelectric conversion element CCNE2, GPX4, PPOX PTGS2 1554/4885MAPT 4514/4885NPSR1 2705/4885
US-20120016147-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER PAH, MAOA, AHR PTGS2 849/4885MAPT 2638/4885NPSR1 4275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.