Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NCEH1 | Q6PIU2 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017843 | 1.00 | RAB9A (0.38) | RAB9AKDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL9017866 | 0.87 | MEN1 (0.41) | RAB9AKDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9017862 | 0.87 | MEN1 (0.41) | RAB9AKDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9017910 | 0.87 | NCEH1 (0.37) | RAB9AKDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL9017888 | 0.87 | BCHE (0.35) | RAB9AKDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL9017883 | 0.86 | KDM4E (0.36) | RAB9AKDM4ESMN1; SMN2GAAALDH1A1 | |
| SCHEMBL9017886 | 0.86 | KDM4E (0.36) | RAB9AKDM4ESMN1; SMN2GAAALDH1A1 | |
| SCHEMBL9017939 | 0.85 | NCEH1 (0.34) | RAB9AKDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL9017940 | 0.85 | NCEH1 (0.34) | RAB9AKDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL9017908 | 0.84 | KDM4E (0.39) | KDM4ELMNAGAAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477903-B1 | Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1996-04-03 | — | — | EP | disclosed |
| EP-0477903-A2 | Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-04-01 | — | — | EP | disclosed |