Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017940 | 1.00 | NCEH1 (0.34) | NCEH1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9017921 | 0.91 | MAPT (0.37) | NCEH1ALDH1A1LMNASMN1; SMN2BCHE | |
| SCHEMBL9017917 | 0.91 | MAPT (0.37) | NCEH1ALDH1A1LMNASMN1; SMN2BCHE | |
| SCHEMBL9017888 | 0.90 | BCHE (0.35) | NCEH1KDM4EALDH1A1HPGDHSD17B10 | |
| Maleic Acid SCHEMBL9017929 | 0.86 | MAPT (0.34) | NCEH1KDM4EALDH1A1L3MBTL1LMNA | |
| Fumaric Acid SCHEMBL9017933 | 0.86 | MAPT (0.34) | NCEH1KDM4EALDH1A1L3MBTL1LMNA | |
| SCHEMBL9017941 | 0.86 | NCEH1 (0.37) | NCEH1PDE4BLMNABCHEACHE | |
| SCHEMBL9017843 | 0.85 | RAB9A (0.38) | NCEH1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9017846 | 0.85 | RAB9A (0.38) | NCEH1KDM4EALDH1A1HPGDHSD17B10 | |
| Maleic Acid SCHEMBL9017901 | 0.82 | KDM4E (0.34) | NCEH1KDM4EL3MBTL1BCHEMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477903-B1 | Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1996-04-03 | — | — | EP | disclosed |