Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017886 | 1.00 | KDM4E (0.36) | KDM4EL3MBTL1KMT2AALDH1A1ACHE | |
| SCHEMBL9017903 | 0.87 | KDM4E (0.39) | KDM4EL3MBTL1KMT2AALDH1A1GAA | |
| SCHEMBL9017908 | 0.87 | KDM4E (0.39) | KDM4EL3MBTL1KMT2AALDH1A1GAA | |
| SCHEMBL9017846 | 0.86 | RAB9A (0.38) | KDM4EL3MBTL1ALDH1A1GAAHSD17B10 | |
| SCHEMBL9017843 | 0.86 | RAB9A (0.38) | KDM4EL3MBTL1ALDH1A1GAAHSD17B10 | |
| SCHEMBL9017844 | 0.84 | HSP90AA1 (0.42) | KDM4EKMT2AALDH1A1ACHEGAA | |
| SCHEMBL9017842 | 0.84 | HSP90AA1 (0.42) | KDM4EKMT2AALDH1A1ACHEGAA | |
| SCHEMBL9017866 | 0.82 | MEN1 (0.41) | KDM4EL3MBTL1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL9017862 | 0.82 | MEN1 (0.41) | KDM4EL3MBTL1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL9679849 | 0.81 | LIPE (0.40) | KDM4EKMT2AALDH1A1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477903-B1 | Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1996-04-03 | — | — | EP | disclosed |