Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | G6PC1 | P35575 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017877 | 1.00 | CHRM4 (0.40) | CHRM4DRD2HTR7G6PC1SMN1; SMN2 | |
| Dimethylcarbate SCHEMBL9679808 | 0.95 | CHRM4 (0.41) | CHRM4DRD2HTR7G6PC1SMN1; SMN2 | |
| Dimethylcarbate SCHEMBL9679824 | 0.95 | CHRM4 (0.41) | CHRM4DRD2HTR7G6PC1SMN1; SMN2 | |
| SCHEMBL9017856 | 0.79 | ALDH1A1 (0.35) | SMN1; SMN2GAAPOLBMAPTCYP2C19 | |
| SCHEMBL9017850 | 0.79 | ALDH1A1 (0.35) | SMN1; SMN2GAAPOLBMAPTCYP2C19 | |
| SCHEMBL9017935 | 0.78 | TSHR (0.46) | CHRM4DRD2HTR7SMN1; SMN2GAA | |
| SCHEMBL9017937 | 0.78 | TSHR (0.46) | CHRM4DRD2HTR7SMN1; SMN2GAA | |
| Dimethylcarbate SCHEMBL9679433 | 0.77 | ALDH1A1 (0.37) | SMN1; SMN2GAAPOLBMAPTCYP2C19 | |
| Dimethylcarbate SCHEMBL9679440 | 0.77 | ALDH1A1 (0.37) | SMN1; SMN2GAAPOLBMAPTCYP2C19 | |
| SCHEMBL9017915 | 0.77 | NPSR1 (0.39) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477903-B1 | Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1996-04-03 | — | — | EP | disclosed |
| EP-0477903-A2 | Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-04-01 | — | — | EP | disclosed |