Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017937 | 1.00 | TSHR (0.46) | TSHRCHRM4DRD2HTR7ABHD6 | |
| SCHEMBL9017843 | 0.82 | RAB9A (0.38) | TSHRNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL9017846 | 0.82 | RAB9A (0.38) | TSHRNPC1RAB9AKDM4ESMN1; SMN2 | |
| Dimethylcarbate SCHEMBL9679824 | 0.81 | CHRM4 (0.41) | TSHRCHRM4DRD2HTR7ROCK1 | |
| Dimethylcarbate SCHEMBL9679808 | 0.81 | CHRM4 (0.41) | TSHRCHRM4DRD2HTR7ROCK1 | |
| SCHEMBL9017941 | 0.81 | NCEH1 (0.37) | TSHRKDM6BKDM4CLMNA | |
| SCHEMBL9017888 | 0.80 | BCHE (0.35) | RAB9AKDM4ESMN1; SMN2GAALMNA | |
| Maleic Acid SCHEMBL9017901 | 0.79 | KDM4E (0.34) | TSHRKDM4EKDM6BKDM4C | |
| SCHEMBL9017880 | 0.78 | CHRM4 (0.40) | TSHRCHRM4DRD2HTR7ROCK1 | |
| SCHEMBL9017877 | 0.78 | CHRM4 (0.40) | TSHRCHRM4DRD2HTR7ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477903-B1 | Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1996-04-03 | — | — | EP | disclosed |