Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 3/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.35 |
| ▸ | G6PC1 | P35575 | 2/20 | 0.35 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylcarbate SCHEMBL9679824 | 1.00 | CHRM4 (0.41) | CHRM4DRD2HTR7CYP2C19LMNA | |
| SCHEMBL9017880 | 0.95 | CHRM4 (0.40) | CHRM4DRD2HTR7CYP2C19LMNA | |
| SCHEMBL9017877 | 0.95 | CHRM4 (0.40) | CHRM4DRD2HTR7CYP2C19LMNA | |
| Dimethylcarbate SCHEMBL9679440 | 0.84 | ALDH1A1 (0.37) | CYP2C19GAANPC1RAB9AKDM6B | |
| Dimethylcarbate SCHEMBL9679433 | 0.84 | ALDH1A1 (0.37) | CYP2C19GAANPC1RAB9AKDM6B | |
| SCHEMBL9017935 | 0.81 | TSHR (0.46) | CHRM4DRD2HTR7CYP2C19LMNA | |
| SCHEMBL9017937 | 0.81 | TSHR (0.46) | CHRM4DRD2HTR7CYP2C19LMNA | |
| Dimethylcarbate SCHEMBL9680336 | 0.79 | KDM6B (0.34) | KDM6BKDM4C | |
| Dimethylcarbate SCHEMBL9680344 | 0.79 | KDM6B (0.34) | KDM6BKDM4C | |
| SCHEMBL9679398 | 0.76 | ALDH1A1 (0.37) | CHRM4CYP2C19LMNAGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477903-A2 | Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-04-01 | — | — | EP | disclosed |