Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LATS1 | O95835 | 1/20 | 0.34 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017915 | 1.00 | NPSR1 (0.39) | NPSR1LATS1LATS2CNR1CNR2 | |
| SCHEMBL9017925 | 0.82 | MAPT (0.35) | CNR1CNR2MAPT | |
| SCHEMBL9017927 | 0.82 | MAPT (0.35) | CNR1CNR2MAPT | |
| SCHEMBL9679870 | 0.81 | — | — | |
| SCHEMBL9679866 | 0.81 | — | — | |
| SCHEMBL9017850 | 0.80 | ALDH1A1 (0.35) | NPSR1MAPTKMT2A | |
| SCHEMBL9017856 | 0.80 | ALDH1A1 (0.35) | NPSR1MAPTKMT2A | |
| SCHEMBL9017941 | 0.78 | NCEH1 (0.37) | NPSR1MAPTKDM6BKDM4C | |
| Dimethylcarbate SCHEMBL9681187 | 0.78 | MAPT (0.36) | MAPTKDM6BKDM4C | |
| Dimethylcarbate SCHEMBL9681182 | 0.78 | MAPT (0.36) | MAPTKDM6BKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477903-B1 | Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1996-04-03 | — | — | EP | disclosed |
| EP-0477903-A2 | Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-04-01 | — | — | EP | disclosed |