Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.31 |
| ▸ | CES1 | P23141 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 3/20 | 0.31 |
| ▸ | MMP9 | P14780 | 3/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 2/20 | 0.30 |
| ▸ | MMP13 | P45452 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034665 | 0.86 | CES2 (0.33) | CES2CES1MMP2MMP9MMP3 | |
| SCHEMBL8027900 | 0.84 | PTGS1 (0.35) | CES2CES1MMP2MMP9MMP3 | |
| SCHEMBL7755593 | 0.78 | KCNH2 (0.32) | MEN1KMT2A | |
| SCHEMBL8732796 | 0.77 | KCNH2 (0.34) | MEN1KMT2AMMP2MMP9MMP3 | |
| SCHEMBL7759523 | 0.76 | CHRM2 (0.33) | MEN1KMT2A | |
| SCHEMBL8021312 | 0.75 | MEN1 (0.32) | MEN1CYP2C9KMT2A | |
| SCHEMBL8031171 | 0.75 | PTGS2 (0.33) | MEN1KMT2ACES2CES1 | |
| SCHEMBL8449305 | 0.74 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL8455937 | 0.73 | DNM1 (0.34) | MEN1KMT2ACES2CES1 | |
| SCHEMBL8021470 | 0.73 | GRM2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8119974-A | — | — | None | — | — | JP | disclosed |
| JP-H08119974-A | SILASPIRO COMPOUND, ITS PRODUCTION AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME COMPOUND | SHIN ETSU CHEM CO LTD | 1996-05-14 | — | — | JP | disclosed |