Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | FLT1 | P17948 | 2/20 | 0.47 |
| ▸ | FLT4 | P35916 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018104 | 0.95 | BCL2L1 (0.48) | BCL2L1MCL1PPARASMN1; SMN2NPC1 | |
| SCHEMBL9018511 | 0.90 | KMT2A (0.51) | BCL2L1MCL1PPARASMN1; SMN2NPC1 | |
| SCHEMBL9018506 | 0.90 | PPARA (0.56) | BCL2L1MCL1PPARASMN1; SMN2NPC1 | |
| SCHEMBL9018305 | 0.90 | BCL2L1 (0.46) | BCL2L1MCL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9018417 | 0.90 | NPC1 (0.46) | BCL2L1MCL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9018032 | 0.89 | HSP90AA1 (0.46) | BCL2L1MCL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9017979 | 0.89 | PPARA (0.50) | BCL2L1MCL1PPARASMN1; SMN2NPC1 | |
| SCHEMBL9018220 | 0.89 | PPARA (0.50) | BCL2L1MCL1PPARASMN1; SMN2NPC1 | |
| SCHEMBL9018347 | 0.88 | EGFR (0.53) | BCL2L1MCL1PPARASMN1; SMN2NPC1 | |
| SCHEMBL9139097 | 0.87 | BCL2L1 (0.55) | BCL2L1MCL1PPARASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |