Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018104 | 0.93 | BCL2L1 (0.48) | KMT2AMEN1RAB9ANPC1P4HTM | |
| SCHEMBL9018237 | 0.93 | CA1 (0.55) | KMT2AMEN1RAB9ANPC1BCL2L1 | |
| SCHEMBL9018076 | 0.93 | ALDH1A1 (0.49) | KMT2AMEN1P4HTMOPRK1OPRM1 | |
| SCHEMBL9018298 | 0.91 | PTPN1 (0.55) | KMT2AMEN1P4HTMBCL2L1MCL1 | |
| SCHEMBL9018065 | 0.90 | BCL2L1 (0.54) | RAB9ANPC1PPARABCL2L1MCL1 | |
| SCHEMBL9018260 | 0.90 | KMT2A (0.54) | KMT2AMEN1RAB9ANPC1P4HTM | |
| SCHEMBL9018305 | 0.90 | BCL2L1 (0.46) | KMT2AMEN1RAB9ANPC1P4HTM | |
| SCHEMBL9018057 | 0.90 | KMT2A (0.58) | KMT2AMEN1RAB9ANPC1P4HTM | |
| SCHEMBL9018112 | 0.89 | LMNA (0.51) | KMT2AMEN1RAB9ANPC1PPARA | |
| SCHEMBL9018402 | 0.89 | POLB (0.45) | KMT2AMEN1RAB9ANPC1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |