Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018026 | 0.93 | P4HTM (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2EGFR | |
| SCHEMBL9018149 | 0.92 | ALDH1A1 (0.43) | MEN1KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL9018285 | 0.92 | ALDH1A1 (0.43) | MEN1KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL9018067 | 0.91 | LMNA (0.40) | MEN1KMT2APOLBALDH1A1EGFR | |
| SCHEMBL9018480 | 0.91 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2P4HTMOPRM1 | |
| SCHEMBL9018138 | 0.91 | ACACB (0.44) | MEN1KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL9018127 | 0.90 | PPARA (0.49) | MEN1KMT2AALDH1A1SMN1; SMN2EGFR | |
| SCHEMBL9017984 | 0.90 | ALDH1A1 (0.47) | POLBALDH1A1EGFRP4HTMOPRM1 | |
| SCHEMBL9018557 | 0.90 | MAPT (0.51) | MEN1KMT2ASMN1; SMN2LMNATP53 | |
| SCHEMBL9018339 | 0.90 | PPARA (0.49) | MEN1KMT2AALDH1A1SMN1; SMN2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |