Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA7 | P43166 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018182 | 0.93 | CA1 (0.54) | CA1CA2CA7CA9CA14 | |
| SCHEMBL9018568 | 0.92 | ALDH1A1 (0.54) | CA1CA2CA7CA9CA14 | |
| SCHEMBL9018194 | 0.90 | TSHR (0.56) | CA1CA2CA7CA9CA14 | |
| SCHEMBL7871641 | 0.90 | CA1 (0.56) | CA1CA2CA7CA9CA14 | |
| SCHEMBL7862780 | 0.90 | CA1 (0.56) | CA1CA2CA7CA9CA14 | |
| SCHEMBL9018057 | 0.89 | KMT2A (0.58) | ALDH1A1MAPTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9018029 | 0.88 | MEN1 (0.50) | CA1CA2CA9ALDH1A1MAPT | |
| SCHEMBL7870510 | 0.88 | CA1 (0.56) | CA1CA2CA7CA9CA14 | |
| SCHEMBL9018049 | 0.87 | MAPT (0.54) | CA1CA2CA9MAPTLMNA | |
| SCHEMBL9018181 | 0.87 | MAPT (0.54) | CA1CA2CA9MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |