Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018275 | 0.92 | ACKR3 (0.41) | MEN1KMT2ACYP2C19MAPTLMNA | |
| SCHEMBL9018074 | 0.92 | MAPT (0.45) | MEN1KMT2ACYP2C19MAPTLMNA | |
| SCHEMBL9018250 | 0.90 | EPHX2 (0.43) | CYP2C19MAPTLMNACYP3A4HTR1A | |
| SCHEMBL9018284 | 0.89 | MEN1 (0.38) | MEN1KMT2ACYP2C19MAPTLMNA | |
| SCHEMBL9018301 | 0.88 | CA1 (0.41) | MAPTLMNASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL9018406 | 0.86 | RAB9A (0.45) | MEN1KMT2AMAPTLMNANFKB1 | |
| SCHEMBL9018435 | 0.86 | ALDH1A1 (0.39) | KMT2AALDH1A1 | |
| SCHEMBL7874653 | 0.85 | KMT2A (0.41) | MEN1KMT2ACYP2C19MAPTLMNA | |
| SCHEMBL9018505 | 0.85 | MAPT (0.50) | MEN1KMT2AMAPTLMNANFKB1 | |
| SCHEMBL7867890 | 0.85 | POLB (0.40) | MEN1KMT2ACYP2C19MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |