Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21628078 | 0.89 | REN (0.56) | RENHDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL3897221 | 0.87 | LMNA (0.52) | RENMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL671194 | 0.84 | REN (0.55) | RENHDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL2568643 | 0.83 | MEN1 (0.43) | RENMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL16333819 | 0.82 | REN (0.54) | RENHDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL13723381 | 0.82 | REN (0.54) | RENHDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL11208970 | 0.82 | REN (0.50) | RENHDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL21326213 | 0.82 | CCR6 (0.56) | RENHDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL4207867 | 0.81 | HDAC1 (0.57) | RENHDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL8773510 | 0.81 | CNR2 (0.64) | HDAC1LMNAPKMCNR2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041493-A1 | AMINOQUINOLINIUM SALTS, METHODS OF THEIR PRODUCTION AND THEIR USE AS ACTIVE AGENTS FOR BIOTECHNOLOGICAL AND MEDICAL APPLICATIONS AGAINST BINARY TOXINS | JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG (DE) | 2012-04-05 | — | — | WO | disclosed |