Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16333819 | 0.98 | REN (0.54) | RENHDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL13723381 | 0.98 | REN (0.54) | RENHDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL4207867 | 0.94 | HDAC1 (0.57) | RENHDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL21628078 | 0.90 | REN (0.56) | RENHDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL7778139 | 0.88 | FOLH1 (0.54) | RENHDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL26985914 | 0.87 | ALOX5 (0.50) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL26985651 | 0.87 | ALOX5 (0.51) | RENHDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL766565 | 0.86 | L3MBTL1 (0.58) | RENHDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL26985835 | 0.86 | TDP1 (0.53) | RENHDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL8328142 | 0.84 | HDAC1 (0.47) | RENHDAC1HDAC6HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12600699-B2 | Thiosemicarbazates and uses thereof | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2026-04-14 | — | — | US | disclosed |
| US-20230111252-A1 | THIOSEMICARBAZATES AND USES THEREOF | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2023-04-13 | — | — | US | disclosed |
| EP-1549309-A4 | SOMATOSTATIN ANALOGUE COMPOUNDS | CHEMBRIDGE RES LAB INC (US) | 2006-05-17 | — | — | EP | disclosed |
| EP-1549309-A2 | SOMATOSTATIN ANALOGUE COMPOUNDS | ChemBridge Research Laboratories, Inc. (US) | 2005-07-06 | — | — | EP | disclosed |
| US-6872827-B2 | Somatostatin analogue compounds | CHEMBRIDGE RESEARCH LABORATORIES, INC. (US) | 2005-03-29 | — | — | US | disclosed |
| US-20040019069-A1 | Somatostatin analogue compounds | CHEMBRIDGE CORPORATION | 2004-01-29 | — | — | US | disclosed |
| WO-2003090677-A2 | SOMATOSTATIN ANALOGUE COMPOUNDS | CHEMBRIDGE RESEARCH LAB., LLC (US) | 2003-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230111252-A1 | THIOSEMICARBAZATES AND USES THEREOF | TST, ABAT, AADAC | REN 1623/4885HDAC1 547/4885HDAC6 291/4885 |
| US-12600699-B2 | Thiosemicarbazates and uses thereof | MET, THRB, ABAT | REN 511/4885HDAC1 1231/4885HDAC6 1070/4885 |
| US-20040019069-A1 | Somatostatin analogue compounds | SSTR2, SSTR1, SSTR4 | REN 59/4885HDAC1 1411/4885HDAC6 1435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.