Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018129 | 0.93 | CA1 (0.46) | ALDH1A1OPRM1OPRD1OPRK1POLB | |
| SCHEMBL9018198 | 0.93 | OPRM1 (0.40) | ALDH1A1OPRM1OPRD1OPRK1POLB | |
| SCHEMBL9018108 | 0.93 | ALDH1A1 (0.44) | ALDH1A1OPRM1OPRD1OPRK1POLB | |
| SCHEMBL9018313 | 0.93 | ALDH1A1 (0.44) | ALDH1A1OPRM1OPRD1OPRK1POLB | |
| SCHEMBL9018211 | 0.93 | ALDH1A1 (0.46) | ALDH1A1OPRM1OPRD1OPRK1POLB | |
| SCHEMBL9018110 | 0.92 | ALDH1A1 (0.46) | ALDH1A1OPRM1OPRD1OPRK1POLB | |
| SCHEMBL9017989 | 0.92 | NPC1 (0.48) | OPRM1OPRD1OPRK1LMNAP4HTM | |
| SCHEMBL9018125 | 0.91 | HSD17B10 (0.48) | ALDH1A1POLBLMNARAB9A | |
| SCHEMBL9018380 | 0.91 | MEN1 (0.46) | OPRM1OPRD1OPRK1LMNAP4HTM | |
| SCHEMBL9018484 | 0.90 | POLB (0.49) | ALDH1A1OPRM1OPRD1OPRK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |