Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 5/20 | 0.43 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.43 |
| ▸ | PDE2A | O00408 | 3/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8612520 | 0.94 | SLC9A1 (0.40) | SLC9A1SLC9A2PDE2AKCNK3KCNK9 | |
| SCHEMBL12569789 | 0.85 | CHEK1 (0.43) | PDE2AKCNK3KCNK9EPHX1 | |
| SCHEMBL9018694 | 0.82 | SLC9A1 (0.44) | SLC9A1 | |
| SCHEMBL9018732 | 0.81 | FFAR4 (0.40) | SLC9A1 | |
| SCHEMBL12569956 | 0.80 | IGF2BP2 (0.49) | PDE2AKCNK3KCNK9 | |
| SCHEMBL9018679 | 0.80 | NOS3 (0.40) | SLC9A1EPHX1 | |
| SCHEMBL9018672 | 0.80 | PIM1 (0.37) | SLC9A1EPHX1 | |
| SCHEMBL9018665 | 0.80 | SLC9A1 (0.48) | SLC9A1SLC9A2PDE2AEPHX1 | |
| SCHEMBL9018666 | 0.78 | PIM1 (0.40) | SLC9A1PDE2A | |
| SCHEMBL8610911 | 0.78 | CFTR (0.50) | SLC9A1SLC9A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743301-A2 | Benzoylguanidines containing fluorine | MERCK PATENT GmbH (DE) | 1996-11-20 | — | — | EP | disclosed |