Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8610216 | 0.92 | MRGPRX4 (0.39) | FFAR4FFAR1PIM1ABL1BRAF | |
| SCHEMBL9018666 | 0.88 | PIM1 (0.40) | FFAR4FFAR1PIM1PLAUSLC9A1 | |
| SCHEMBL9018694 | 0.84 | SLC9A1 (0.44) | SLC9A1 | |
| SCHEMBL30468358 | 0.83 | CHEK1 (0.47) | FFAR4FFAR1PIM1ABL1BRAF | |
| SCHEMBL13407882 | 0.83 | CHEK1 (0.47) | FFAR4FFAR1PIM1ABL1BRAF | |
| SCHEMBL9018679 | 0.82 | NOS3 (0.40) | PIM1SLC9A1GRIN2BKDM4EGAA | |
| SCHEMBL9018672 | 0.82 | PIM1 (0.37) | PIM1PLAUSLC9A1 | |
| SCHEMBL8611570 | 0.81 | CFTR (0.40) | PIM1ABL1EPHX2CHEK1KDM4E | |
| SCHEMBL9018686 | 0.81 | SLC9A1 (0.43) | SLC9A1 | |
| SCHEMBL9018718 | 0.80 | SLC9A1 (0.41) | PIM1SLC9A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743301-A2 | Benzoylguanidines containing fluorine | MERCK PATENT GmbH (DE) | 1996-11-20 | — | — | EP | disclosed |