Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613343 | 0.91 | CFTR (0.53) | SLC9A1KCNH2PLAUCES2CNR2 | |
| SCHEMBL9018707 | 0.83 | SLC9A1 (0.46) | SLC9A1PLAUCES2CNR2CNR1 | |
| SCHEMBL9018662 | 0.83 | CES2 (0.62) | SLC9A1KCNH2PLAUCES2 | |
| SCHEMBL9018680 | 0.82 | SLC9A1 (0.43) | SLC9A1PLAUCES2 | |
| SCHEMBL9018685 | 0.82 | CES2 (0.49) | SLC9A1KCNH2PLAUCES2 | |
| SCHEMBL5323409 | 0.82 | CES2 (0.50) | CES2 | |
| Hydrochloric Acid SCHEMBL8393438 | 0.81 | CES2 (0.60) | SLC9A1KCNH2PLAUCES2 | |
| SCHEMBL9018689 | 0.81 | JAK2 (0.48) | SLC9A1PLAUCES2CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL8393445 | 0.81 | SLC9A1 (0.45) | SLC9A1PLAUCES2CNR2CNR1 | |
| SCHEMBL8116935 | 0.81 | SLC9A1 (0.50) | SLC9A1PLAUCNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743301-A2 | Benzoylguanidines containing fluorine | MERCK PATENT GmbH (DE) | 1996-11-20 | — | — | EP | disclosed |