Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 3/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PNLIP | P16233 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018667 | 0.87 | SLC9A1 (0.46) | SLC9A1 | |
| SCHEMBL9018720 | 0.84 | SLC9A1 (0.41) | SLC9A1 | |
| SCHEMBL9018712 | 0.83 | SLC9A1 (0.47) | SLC9A1 | |
| SCHEMBL9018721 | 0.82 | PLAU (0.41) | SLC9A1MC4RKCNH2PLAU | |
| SCHEMBL8609863 | 0.81 | SLC9A1 (0.40) | SLC9A1 | |
| SCHEMBL9018698 | 0.79 | SLC9A1 (0.40) | SLC9A1KCNH2PLAU | |
| SCHEMBL8612510 | 0.78 | SLC9A1 (0.37) | SLC9A1 | |
| SCHEMBL8610762 | 0.77 | SLC9A1 (0.47) | SLC9A1 | |
| SCHEMBL9018711 | 0.77 | PLAU (0.41) | SLC9A1MC4RKCNH2PLAU | |
| SCHEMBL8609018 | 0.75 | SLC9A1 (0.36) | SLC9A1MC4RKCNH2PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743301-A2 | Benzoylguanidines containing fluorine | MERCK PATENT GmbH (DE) | 1996-11-20 | — | — | EP | disclosed |