Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | PPOX | P50336 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8610762 | 0.92 | SLC9A1 (0.47) | SLC9A1MEN1TTRPPOXKMT2A | |
| SCHEMBL9018736 | 0.85 | SLC9A1 (0.40) | SLC9A1LMNA | |
| SCHEMBL9018722 | 0.83 | SLC9A1 (0.45) | SLC9A1 | |
| SCHEMBL9018726 | 0.81 | SLC9A1 (0.50) | SLC9A1TDP1F2PRSS1PRSS2 | |
| SCHEMBL9018667 | 0.80 | SLC9A1 (0.46) | SLC9A1 | |
| SCHEMBL8608691 | 0.79 | SLC9A1 (0.40) | SLC9A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL9018718 | 0.78 | SLC9A1 (0.41) | SLC9A1MEN1TTRPPOXKMT2A | |
| SCHEMBL9018720 | 0.77 | SLC9A1 (0.41) | SLC9A1 | |
| SCHEMBL8610045 | 0.76 | SLC9A1 (0.48) | SLC9A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL21066355 | 0.74 | ALDH1A1 (0.41) | MEN1TTRPPOXKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743301-A2 | Benzoylguanidines containing fluorine | MERCK PATENT GmbH (DE) | 1996-11-20 | — | — | EP | disclosed |