SCHEMBL9018730

SCHEMBL9018730

CS(=O)(=O)c1cc(C(=O)N=C(N)N)ccc1OC(F)F

nearest known ligand 0.72

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 3/20 0.61
SLC9A2 Q9UBY0 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8610910 0.95 SLC9A1 (0.56) SLC9A1SLC9A2
SCHEMBL9189978 0.84 SLC9A1 (0.63) SLC9A1SLC9A2
Hydrochloric Acid SCHEMBL8816495 0.83 SLC9A1 (0.61) SLC9A1SLC9A2
SCHEMBL9018675 0.82 SLC9A1 (0.57) SLC9A1SLC9A2
SCHEMBL9018728 0.82 SLC9A1 (0.57) SLC9A1SLC9A2
SCHEMBL9018688 0.81 SLC9A1 (0.67) SLC9A1
SCHEMBL9018697 0.81 PKM (0.50)
SCHEMBL8573607 0.80 SLC9A1 (0.78) SLC9A1SLC9A2
SCHEMBL9196826 0.80 SLC9A1 (0.62) SLC9A1SLC9A2
SCHEMBL8743797 0.79 SLC9A1 (0.54) SLC9A1SLC9A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0743301-A2 Benzoylguanidines containing fluorine MERCK PATENT GmbH (DE) 1996-11-20 EP disclosed