Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | TPMT | P51580 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8610910 | 0.88 | SLC9A1 (0.56) | — | |
| SCHEMBL2562181 | 0.86 | NPSR1 (0.54) | PKMNPSR1RAB9AHTTLMNA | |
| SCHEMBL9018730 | 0.81 | SLC9A1 (0.61) | — | |
| SCHEMBL2565798 | 0.81 | PKM (0.73) | PKMNPSR1RAB9AHTTLMNA | |
| SCHEMBL9018714 | 0.79 | PKM (0.50) | PKMNPSR1RAB9AHTTLMNA | |
| SCHEMBL9018673 | 0.79 | PKM (0.50) | PKMNPSR1RAB9AHTTLMNA | |
| SCHEMBL1029279 | 0.79 | PDE4A (0.59) | RAB9AHTTLMNAMAPK1CA12 | |
| SCHEMBL9018709 | 0.78 | SLC9A1 (0.39) | NPSR1KDM4E | |
| SCHEMBL17020098 | 0.78 | HTT (0.49) | RAB9AHTTLMNAMAPK1CA12 | |
| SCHEMBL6294909 | 0.77 | TSHR (0.60) | PKMNPSR1RAB9ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743301-A2 | Benzoylguanidines containing fluorine | MERCK PATENT GmbH (DE) | 1996-11-20 | — | — | EP | disclosed |