Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | RPS6KB2 | Q9UBS0 | 2/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23410331 | 0.82 | FGFR4 (0.51) | FGFR4MAPTRPS6KB2FGFR1FGFR2 | |
| SCHEMBL4892092 | 0.82 | MAPT (0.55) | FGFR4MAPTRPS6KB2PIN1HTT | |
| SCHEMBL18766140 | 0.74 | FGFR4 (0.49) | FGFR4MAPTRPS6KB2FGFR1FGFR2 | |
| SCHEMBL29392518 | 0.74 | FGFR4 (0.49) | FGFR4MAPTRPS6KB2FGFR1FGFR2 | |
| SCHEMBL29535826 | 0.74 | MAPT (0.54) | FGFR4MAPTRPS6KB2FGFR1FGFR2 | |
| SCHEMBL22719050 | 0.74 | MAPT (0.54) | FGFR4MAPTRPS6KB2FGFR1FGFR2 | |
| SCHEMBL1600402 | 0.74 | PIN1 (0.65) | FGFR4MAPTRPS6KB2PIN1HTT | |
| SCHEMBL16037191 | 0.74 | ALDH1A1 (0.61) | MAPTHTTPOLBKMT2AMEN1 | |
| SCHEMBL9984336 | 0.72 | MAPT (0.52) | FGFR4MAPTRPS6KB2FGFR1FGFR2 | |
| SCHEMBL29636874 | 0.72 | MAPT (0.59) | FGFR4MAPTRPS6KB2FGFR1FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041476-A1 | PYRIDINE AND ISOQUINOLINE DERIVATIVES AS SYK- AND JAK-KINASE INHIBITORS | ALMIRALL, S.A. (ES) | 2012-04-05 | — | — | WO | disclosed |